Antonis Kattamis Selected Research

Deferasirox

1/2022	An open-label, multicenter, efficacy, and safety study of deferasirox in iron-overloaded patients with non-transfusion-dependent thalassemia (THETIS): 5-year results.
6/2020	Evaluation of the efficacy and safety of deferiprone compared with deferasirox in paediatric patients with transfusion-dependent haemoglobinopathies (DEEP-2): a multicentre, randomised, open-label, non-inferiority, phase 3 trial.
1/2020	Two-year long safety and efficacy of deferasirox film-coated tablets in patients with thalassemia or lower/intermediate risk MDS: phase 3 results from a subset of patients previously treated with deferasirox in the ECLIPSE study.
11/2018	Patient-reported outcomes from a randomized phase II study of the deferasirox film-coated tablet in patients with transfusion-dependent anemias.
9/2018	Optimising management of deferasirox therapy for patients with transfusion-dependent thalassaemia and lower-risk myelodysplastic syndromes.
7/2017	Electrophysiological assessment for early detection of retinal dysfunction in β-thalassemia major patients.
5/2017	New film-coated tablet formulation of deferasirox is well tolerated in patients with thalassemia or lower-risk MDS: Results of the randomized, phase II ECLIPSE study.
1/2016	Efficacy and safety of iron-chelation therapy with deferoxamine, deferiprone, and deferasirox for the treatment of iron-loaded patients with nontransfusion-dependent thalassemia syndromes.
6/2015	Effects of deferasirox-deferoxamine on myocardial and liver iron in patients with severe transfusional iron overload.
1/2015	Defining serum ferritin thresholds to predict clinically relevant liver iron concentrations for guiding deferasirox therapy when MRI is unavailable in patients with non-transfusion-dependent thalassaemia.

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Antonis Kattamis Research Topics

Disease

31	Thalassemia 11/2022 - 01/2005
28	Iron Overload 01/2022 - 05/2006
21	beta-Thalassemia (Cooley's Anemia) 01/2021 - 06/2004
9	Neoplasms (Cancer) 01/2022 - 12/2014
6	Anemia 01/2021 - 06/2006
5	Siderosis 06/2015 - 01/2005
4	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 01/2020 - 05/2017
3	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 11/2021 - 01/2018
3	Diamond-Blackfan Anemia (Anemia, Diamond Blackfan) 01/2021 - 01/2011
3	Agranulocytosis (Granulocytopenia) 06/2020 - 01/2005
3	Sickle Cell Anemia (Hemoglobin S Disease) 06/2018 - 06/2004
3	Nausea 03/2016 - 07/2011
3	Exanthema (Rash) 08/2012 - 05/2006
2	Inborn Genetic Diseases (Disease, Hereditary) 01/2022 - 01/2021
2	Chronic Disease (Chronic Diseases) 01/2022 - 06/2014
2	Brain Neoplasms (Brain Tumor) 11/2021 - 12/2014
2	Virus Diseases (Viral Diseases) 01/2021 - 10/2010
2	Hemoglobinopathies 12/2020 - 01/2017
2	Diffuse Intrinsic Pontine Glioma 10/2019 - 01/2017
2	Disease Progression 10/2019 - 10/2010
2	Hypoxia (Hypoxemia) 06/2018 - 06/2006
2	Osteoporosis 06/2018 - 12/2015
2	Liver Diseases (Liver Disease) 01/2017 - 10/2010
2	Chronic Hepatitis C 01/2017 - 01/2005
2	Fibrosis (Cirrhosis) 10/2010 - 02/2006
1	Diabetes Mellitus 11/2022
1	Hypochromic Anemia (Chlorosis) 03/2022
1	Rhabdomyosarcoma 01/2022
1	Hemolysis 01/2022
1	Methemoglobinemia 12/2021
1	Intellectual Disability (Idiocy) 01/2021
1	Craniofacial Abnormalities 01/2021
1	Cardiomyopathies (Cardiomyopathy) 01/2021
1	Neutropenia 01/2021
1	Hypertension (High Blood Pressure) 01/2020
1	Pain (Aches) 01/2020
1	Arthralgia (Joint Pain) 01/2020
1	Dizziness (Lightheadedness) 01/2020
1	Body Weight (Weight, Body) 01/2020
1	Aplastic Anemia (Anemia, Hypoplastic) 01/2020
1	Hyperuricemia 01/2020
1	Infections 04/2019
1	Human Influenza (Influenza) 04/2019
1	Fatigue 01/2019
1	Hypothyroidism 01/2019
1	Inflammation (Inflammations) 06/2018

Drug/Important Bio-Agent (IBA)

32	IronIBA 01/2022 - 01/2005
23	Deferasirox FDA Link 01/2022 - 05/2006
8	DeferiproneIBA 01/2022 - 01/2005
7	Deferoxamine (Desferal)FDA LinkGeneric 09/2018 - 01/2005
6	Ferritins (Ferritin)IBA 01/2015 - 01/2005
5	GlobinsIBA 01/2022 - 01/2015
5	Pharmaceutical PreparationsIBA 11/2021 - 01/2011
5	Chelating AgentsIBA 09/2018 - 05/2006
4	HepcidinsIBA 01/2021 - 06/2006
3	Hemoglobins (Hemoglobin)IBA 12/2021 - 01/2019
3	TabletsIBA 01/2020 - 05/2017
3	AntigensIBA 03/2019 - 09/2014
3	Biomarkers (Surrogate Marker)IBA 12/2017 - 12/2014
3	Isoflurophate (DFP)FDA Link 10/2011 - 01/2005
3	CreatinineIBA 07/2011 - 05/2006
3	Hydroxyurea (Hydrea)FDA LinkGeneric 11/2009 - 06/2004
2	Glucose (Dextrose)FDA LinkGeneric 11/2022 - 01/2021
2	SteroidsIBA 11/2021 - 01/2021
2	luspaterceptIBA 10/2021 - 01/2020
2	Ribosomal Proteins (Ribosomal Protein)IBA 01/2021 - 01/2011
2	dipinacoline glutamateIBA 10/2019 - 01/2017
2	Conjugate VaccinesIBA 03/2019 - 09/2014
2	Antiviral Agents (Antivirals)IBA 01/2017 - 10/2010
2	InterferonsIBA 01/2017 - 01/2005
1	Hemoglobin A2IBA 03/2022
1	Fetal Hemoglobin (Hemoglobin F)IBA 03/2022
1	MethemoglobinIBA 12/2021
1	Antineoplastic Agents (Antineoplastics)IBA 11/2021
1	Cyclophosphamide (Cytoxan)FDA LinkGeneric 11/2021
1	betibeglogene autotemcelIBA 10/2021
1	LigandsIBA 10/2021
1	Activins (Activin)IBA 10/2021
1	Free RadicalsIBA 01/2021
1	metal transporting protein 1 (ferroportin)IBA 01/2021
1	blinatumomabIBA 01/2021
1	Oxygen (Dioxygen)IBA 01/2021
1	eltrombopag FDA Link 01/2020
1	Anti-Bacterial Agents (Antibiotics)IBA 04/2019
1	Oseltamivir (Tamiflu)FDA Link 04/2019
1	VaccinesIBA 03/2019
1	AntibodiesIBA 03/2019
1	ruxolitinibIBA 11/2018
1	Tyrosine (L-Tyrosine)FDA Link 06/2018

Therapy/Procedure

18	Therapeutics 11/2021 - 06/2004
12	Chelation Therapy (Therapy, Chelation) 01/2022 - 04/2010
6	Splenectomy 01/2019 - 10/2006
2	Stem Cell Transplantation 11/2021 - 04/2019
2	Drug Therapy (Chemotherapy) 04/2019 - 01/2019
2	Blood Transfusion (Blood Transfusions) 07/2017 - 05/2006
1	Glycemic Control 11/2022
1	Brachytherapy 01/2022
1	Conservative Treatment 01/2022
1	Radiotherapy 01/2022
1	Erythrocyte Transfusion 12/2020